Annie Duke defeated Erik Seidel 2-1 in the Heads-Up final. She becomes the first woman to win the event and takes home the $500,000 prize. Seidel wins $250,000 for his second place finish.

It was a great night of firsts for women as Duke takes home this title, Katherine Bigelow became the first woman director to win an Oscar for 'Hurt Locker' and a PA here made a sports wager for the first time ever.

Erik Seidel withstood a suck out by Annie Duke and held on to match two, tying up the best-of-three final at 1-1. Match three will start shortly.

Annie Duke took the first match in the best-of-three finals of the Heads-Up Championship. Erik Seidel will need to win two straight to win the title.

In a best of three final, Annie Duke will face Erik Seidel for the 2010 National Heads-Up Championship title.

Updated bracket

Erik Seidel survived his semifinal matchup with Scotty Nguyen and will now face Annie Duke in the finals.

After an hour and a half of play, Annie Duke defeated Dennis Phillips and advanced to the Heads-Up Championship finals where she'll face the winner of Erik Seidel and Scotty Nguyen.

Here are the matchups for the semifinals, scheduled to start at 3:30 p.m. PT.

Semifinals
Erik Seidel vs. Scotty Nguyen
Dennis Phillips vs. Annie Duke

Finals (Best of three)
6 p.m. PT

Updated bracket

Annie Duke survived some major suck outs by Jerry Yang to advance to the semifinals where she'll face Dennis Phillips.

Dennis Phillips has moved into the semifinals, defeating poker legend Doyle Brunson.

The remaining two quarterfinal matches have begun with Annie Duke taking on Jerry Yang and Dennis Phillips playing against poker legend Doyle Brunson.